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Related Experiment Video

Updated: Jun 24, 2026

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Published on: September 30, 2021

Bleeding disorders in adolescents.

Andra H James¹

¹Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University Medical Center, Box 3967, Durham, NC 27710, USA. andra.james@duke.edu

Obstetrics and Gynecology Clinics of North America

|April 7, 2009

Summary

This summary is machine-generated.

Adolescents with heavy menstrual bleeding may have an underlying bleeding disorder. Proper evaluation and hormonal management, with hemostatic therapies if needed, can effectively treat this condition.

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Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells

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Published on: December 27, 2017

Area of Science:

Reproductive endocrinology and hematology

Background:

Adolescents with bleeding disorders frequently experience abnormal reproductive tract bleeding, such as menorrhagia.
While most abnormal bleeding is not due to a bleeding disorder, a higher likelihood exists in affected adolescents.

Purpose of the Study:

To highlight the association between bleeding disorders and abnormal reproductive tract bleeding in adolescents.
To emphasize the importance of proper evaluation for underlying bleeding disorders in adolescents presenting with abnormal uterine bleeding.

Main Methods:

Review of clinical presentations and diagnostic considerations for abnormal reproductive tract bleeding in adolescents.
Discussion of management strategies, including hormonal therapy and hemostatic agents.

Main Results:

Adolescents with bleeding disorders are at increased risk for abnormal reproductive tract bleeding.
Abnormal reproductive tract bleeding in adolescents warrants consideration of an underlying bleeding disorder.

Conclusions:

Most abnormal reproductive tract bleeding in adolescents can be managed effectively.
Hormonal therapy is a primary treatment, supplemented by hemostatic therapies when indicated.