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Altered T cell costimulation during chronic hepatitis B infection

Luisa Barboza1, Siham Salmen, Darrell L Peterson

  • 1Institute of Clinical Immunology, University of Los Andes, Mérida-Venezuela.

Cellular Immunology
|April 7, 2009
PubMed
Summary

Chronic hepatitis B virus (HBV) infection impairs T-cell responses. In chronically infected patients, CD4+ T cells show reduced activation and increased IL-10, hindering viral clearance and promoting persistence.

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