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Updated: Jun 24, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Inferential confusion, obsessive beliefs, and obsessive-compulsive symptoms: a replication and extension
Kevin D Wu1, Frederick Aardema, Kieron P O'Connor
1Northern Illinois University, 311 Psychology-Computer Science Bldg, Department of Psychology, DeKalb, IL 60115, United States. kevinwu@niu.edu
Abstract:
This study replicated and extended previous research regarding utility of an inference-based approach (IBA) to the study of Obsessive-Compulsive Disorder (OCD). The IBA is a model for the development of OCD symptoms through false reasoning. One of its key features is inferential confusion-a form of processing information in which an individual accepts a remote possibility based only on subjective evidence. In a nonclinical sample, this study examined the specificity of relations between the expanded Inferential Confusion Questionnaire (ICQ-EV) and OC symptoms. Results were that the ICQ-EV significantly predicted OC symptoms after controlling for general distress, anxiety, and depression. This finding supports the unique association between inferential confusion and OCD. Further, the ICQ-EV was a stronger predictor of certain OC symptoms than scales from the Obsessive Beliefs Questionnaire, which itself has shown strong relations with OC symptoms. Thus, both inference-based and cognitive appraisal models appear useful for understanding OCD.
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