Familial acquired pigmented streaks in the nail
1University Department of Dermatology, Royal Infirmary, Edinburgh, UK.
Clinical and Experimental Dermatology
|May 1, 1991
Summary
Longitudinal pigmented streaks in nails, also known as melanonychia, can be benign. A biopsy revealed pigmentary incontinence and macrophages, ruling out more serious conditions.
Area of Science:
- Dermatology
- Nail Biology
Background:
- Longitudinal melanonychia presents as pigmented streaks in nails.
- Differential diagnosis includes benign nevi, lentigines, and malignant melanoma.
Observation:
- A 40-year-old male presented with multiple nail streaks.
- His sister had a single nail streak.
- No history of drug use, illness, or other dermatological findings.
Findings:
- Nail matrix biopsy showed pigmentary incontinence.
- Excess macrophages were observed.
- No evidence of nevus or lentigo was found.
Implications:
- This case highlights benign causes of nail pigmentation.
- Understanding nail matrix histology aids in diagnosis.
- Further monitoring may be warranted for persistent nail changes.
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