Bath-water delivery of 8-methoxypsoralen therapy for psoriasis

Twenty-one patients with chronic plaque psoriasis were treated with bath 8-methoxypsoralen (8-MOP) and ultraviolet A (UVA). Clearing was achieved in sixty per cent of patients which was less than would be expected with oral 8-MOP. The treatment was well tolerated and was preferred by those who had previously been treated with oral psoralen. The cumulative dose of UVA was only one-fifth that expected with oral 8-MOP.