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Updated: Jun 24, 2026
Detecting Behavioral Deficits in Rats After Traumatic Brain Injury
Published on: January 30, 2018
Sensitivity and specificity of the Beck Depression Inventory-II in persons with traumatic brain injury
Beeta Y Homaifar1, Lisa A Brenner, Peter M Gutierrez
1Veterans Affairs VISN 19 Mental Illness Research, Education and Clinical Center, Denver, CO, USA.
Objectives:
Our objective was to examine the Beck Depression Inventory-II (BDI-II) in a traumatic brain injury (TBI) sample using a receiver operating characteristic (ROC) curve to determine how well the BDI-II identifies depression. An ROC curve allows for analysis of the sensitivity and specificity of a diagnostic test using various cutoff points to determine the number of true positives, true negatives, false positives, and false negatives.
Design:
This was a secondary analysis of data gathered from an observational study. We examined BDI-II scores in a sample of 52 veterans with remote histories of TBI.
Setting:
This study was completed at a Veterans Affairs (VA) Medical Center.
Participants:
Participants were veterans eligible to receive VA health care services.
Interventions:
Not applicable.
Main Outcome Measures:
Outcome measures included the BDI-II and the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-IV).
Results:
We generated an ROC curve to determine how well the BDI-II identifies depression using the SCID-IV as the criterion standard for diagnosing depression, defined here as a diagnosis of major depressive disorder. Results indicated a cutoff score of at least 19 if one has a mild TBI or at least 35 if one has a moderate or severe TBI. These scores maximize sensitivity (87%) and specificity (79%).
Conclusions:
Clinicians working with persons with TBI can use the BDI-II to determine whether depressive symptoms warrant further assessment.
