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Acromegaly and psoriasis
D J Todd1, D J Eedy, J C McMillan
1Department of Dermatology, Belfast City Hospital, UK.
Clinical and Experimental Dermatology
|May 1, 1991
Summary
A patient with chronic plaque psoriasis experienced remission after treatment for acromegaly caused by a pituitary adenoma. This suggests a potential link between pituitary tumors and severe skin conditions.
Area of Science:
- Endocrinology
- Dermatology
- Oncology
Background:
- Chronic plaque psoriasis is a long-standing autoimmune condition.
- Acromegaly is a hormonal disorder caused by excess growth hormone, often due to a pituitary adenoma.
Observation:
- A 56-year-old male patient presented with both chronic plaque psoriasis and acromegaly.
- The acromegaly was attributed to a large pituitary adenoma.
Findings:
- The patient underwent a hypophysectomy to treat the pituitary adenoma.
- Following the surgery, the patient's chronic plaque psoriasis resolved dramatically within three weeks.
Implications:
- This case highlights a potential etiological link between pituitary adenomas and psoriasis.
- Further research is warranted to explore the hormonal and immunological mechanisms connecting acromegaly and dermatological conditions.
- This finding may open new avenues for psoriasis treatment targeting pituitary function.