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Clinical features of dysplastic nevi
A McBride1, J K Rivers, A W Kopf
1Department of Dermatology, University of Pittsburgh School of Medicine, Pennsylvania.
Dermatologic Clinics
|October 1, 1991
Summary
Clinical features of 100 dysplastic nevi were analyzed. Most large melanocytic nevi in this syndrome present as multicoloured papules or plaques with specific surface characteristics.
Area of Science:
- Dermatology
- Pathology
Background:
- Dysplastic nevi are atypical moles that can indicate an increased risk of melanoma.
- Understanding the clinical spectrum of dysplastic nevi is crucial for accurate diagnosis and patient management.
Purpose of the Study:
- To systematically document and analyze the clinical characteristics of a cohort of dysplastic nevi.
- To identify common and variable features within the spectrum of dysplastic nevus morphology.
Main Methods:
- Tabulation of clinical features from 100 cases of dysplastic nevi.
- Detailed description of morphological attributes, including size, color, elevation, surface texture, and presence of hypertrichosis.
Main Results:
- Significant heterogeneity in clinical features was observed among the 100 dysplastic nevi.
- The predominant type of large (≥8 mm) dysplastic nevus was characterized as a papule or plaque.
- Key features included multicoloration (tan, brown, red, black), slight elevation relative to diameter, a mamillated surface, and absence of hypertrichosis.
Conclusions:
- Dysplastic nevi exhibit a wide range of clinical presentations.
- Specific morphological criteria, such as multicoloration and surface texture, are characteristic of large dysplastic nevi in this cohort.
- An atlas of clinical varieties aids in recognizing these melanocytic nevi.