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Updated: Jun 24, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Noninvasive coronary angiography focusing on calcification: multislice computed tomography compared with magnetic
Christoph Langer1, Andreas Peterschröder, Krista Franzke
1Department of Cardiology, Ruhr University Bochum, Bad Oeynhausen, Germany.
Insights
Multislice computed tomography (MSCT) and magnetic resonance imaging (MRI) were compared for noninvasive coronary angiography. MSCT demonstrated superior accuracy in detecting coronary stenosis, especially in patients with significant calcification.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Medical Diagnostics
Background:
- Coronary calcification poses a significant challenge for noninvasive coronary angiography (CA) using multislice computed tomography (MSCT).
- Magnetic resonance imaging (MRI) is often perceived to have limitations in visualizing calcified lesions.
Purpose of the Study:
- To compare the diagnostic performance of MSCT and MRI for noninvasive coronary angiography.
- To evaluate the impact of coronary calcifications on the accuracy of both imaging modalities.
Main Methods:
- Sixty-eight patients underwent both MSCT and MRI for noninvasive CA prior to conventional angiography.
- Stenosis detection (>=50%) was assessed visually and validated quantitatively.
Main Results:
- MSCT showed higher patient-based performance (sensitivity 96.2%, specificity 95.2%) than MRI (69.2%, 64.3%).
- Segment-based results also favored MSCT (sensitivity 74.7%, specificity 97.8%) over MRI (40%, 93.8%).
- MSCT maintained high accuracy even in patients with advanced calcification (volume score >= 300 microL) and hardening artifacts.
Conclusions:
- MSCT is a more accurate modality for noninvasive coronary angiography compared to MRI.
- MRI offers no significant advantages over MSCT in the presence of advanced coronary calcification.
Objective:
Calcification is a principal problem in noninvasive coronary angiography (CA) performed with multislice computed tomography (MSCT). Magnetic resonance imaging (MRI) supposedly neglects calcium. We compared both modalities.
Methods:
Sixty-eight patients admitted for CA underwent MSCT- and MRI-based noninvasive CA the day before. Stenosis detection (>or=50%) was visually performed and validated by quantitative CA.
Results:
The patient-based overall sensitivity, specificity, positive predictive value, and negative predictive value were 96.2%, 95.2%, 92.6%, and 97.6% for MSCT versus 69.2%, 64.3, 54.5%, 64.3%, and 77.1% for MRI, respectively. The segment-based overall results were 74.7%, 97.8%, 75.7%, and 97.6% for MSCT versus 40%, 93.8%, 37.5%, and 94.4% for MRI, respectively. Investigating the impact of coronary calcifications in the patient group with a volume score of 300 microL or greater resulted in 100%, 80%, 92.3%, and 100% for MSCT versus 70.8%, 86.7%, 89.5%, and 65% for MRI, respectively. The segment group with considerable hardening artifacts resulted in 85.3%, 83.9%, 76.3%, and 90.4% for MSCT versus 52.9%, 92.9%, 81.8%, and 76.5% for MRI, respectively.
Conclusions:
There are no major advantages of MRI in cases of advanced coronary calcification.
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Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...