Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Imaging Studies for Cardiovascular System V: CT

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...

Acute Coronary Syndrome III: Diagnostic Studies

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Off-Label Biliary Stents for Refractory Anastomotic Strictures and Leaks after Esophageal Atresia Repair in Infants.

Endoscopy international open·2026

Same author

Is routine imaging follow-up after LAA closure necessary?

European heart journal. Cardiovascular Imaging·2025

Same author

Rare late rupture of calcified left ventricular aneurysm with pseudoaneurysm formation.

European heart journal. Cardiovascular Imaging·2025

Same author

Left atrial functional impairment as a predictor of atrial fibrillation: insights from cardiac CT.

European radiology·2025

Same author

The Role of Intersectional Stigma in Coronary Artery Disease Among Cisgender Women Aging with HIV.

Behavioral medicine (Washington, D.C.)·2024

Same author

Conduit Flow Compensates for Impaired Left Atrial Passive and Booster Functions in Advanced Diastolic Dysfunction.

Circulation. Cardiovascular imaging·2024

Search research articles

Related Experiment Video

Updated: Jun 24, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

Quantitative evaluation of regional left ventricular function by multidetector computed tomography.

Jonathan Lessick¹, Tsur Ben-Haim, Diab Mutlak

¹Cardiology Department, Rambam Health Care Campus, Haifa, Israel. j_lessick@rambam.health.gov.il

Journal of Computer Assisted Tomography

|April 7, 2009

Summary

This summary is machine-generated.

Quantitative analysis of regional heart function using multidetector computed tomography (MDCT) can effectively differentiate normal, hypokinetic, and akinetic heart segments. This study establishes typical values and optimal thresholds for improved diagnostic accuracy in left ventricular function assessment.

More Related Videos

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging

Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging

Published on: May 24, 2021

Related Experiment Videos

Last Updated: Jun 24, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging

Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging

Published on: May 24, 2021

Area of Science:

Cardiology
Medical Imaging
Quantitative Analysis

Background:

Contemporary workstations enable quantitative analysis of regional function via multidetector computed tomography (MDCT).
Establishing normal values and optimal thresholds is crucial for accurate interpretation of MDCT-derived functional parameters.
Visual assessment of regional myocardial function can be subjective and may benefit from quantitative support.

Purpose of the Study:

To establish typical quantitative values for normal, hypokinetic, and akinetic left ventricular segments using MDCT.
To determine optimal thresholds for differentiating normal from abnormal regional myocardial function.
To assess the utility of quantitative MDCT in mapping left ventricular function.

Main Methods:

Quantitative regional functional parameters from MDCT were compared with visual analysis from MDCT and echocardiography in 33 patients.
Normal values were established to account for segmental variability.
Receiver operating characteristic (ROC) analysis was employed to determine optimal thresholds for differentiating normal and abnormal segments.

Main Results:

Significant differences (P < 0.0001) were observed in end-systolic thickness, thickening, and motion across akinetic, hypokinetic, and normokinetic segments.
Myocardial thickening demonstrated the best performance for differentiation, with an area under the curve of 0.87 and 82% sensitivity and specificity.
Good intraobserver variability was noted, while interobserver variability was moderate.

Conclusions:

Quantitative analysis of regional myocardial function using MDCT is feasible and assists physicians in mapping left ventricular function.
The established typical values and thresholds can aid in the objective assessment of regional heart wall motion abnormalities.
Further refinement of interobserver variability may enhance the clinical utility of this quantitative approach.