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Compliance with and response to hepatitis B vaccination in remaining quilombo communities in Central Brazil
Ana Rita C Motta-Castro1, Selma A Gomes, Clara F T Yoshida
1Departamento de Farmácia-Bioquímica, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brasil.
Abstract:
Compliance with and responses to the hepatitis B vaccine were evaluated in remaining quilombo communities in Central Brazil. A total of 708 individuals who were susceptible to hepatitis B virus infection were invited to participate in the hepatitis B vaccination program in eight communities. Although 567 (80%) individuals received the first dose, only 198 (28%) complied with the full vaccination scheme. Of 148 subjects who agreed to be tested for anti-HBs, 123 (83.1%; 95%CI: 75.9-88.6) responded to the vaccine. A geometric mean titer of 512mIU/mL (95%CI: 342.5-765.3) was found. Male sex and older age were independently associated with non-response. Additional health education programs and alternative hepatitis B vaccine schedules are needed to improve the vaccination coverage in these communities in Central Brazil.
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