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Related Concept Videos

Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
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Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
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Fungal Phylum Ascomycota

Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
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Diversity of Protists IV

Amoebozoa represent a diverse group of terrestrial and aquatic protists that utilize lobe-shaped pseudopodia for locomotion and feeding. This characteristic differentiates them from the Rhizaria, which possess threadlike pseudopodia. The primary classifications within Amoebozoa include gymnamoebas, entamoebas, and the plasmodial and cellular slime molds. Phylogenetic evidence indicates that Amoebozoa diverged from a lineage that ultimately gave rise to fungi and animals.Gymnamoebas and...
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Fungi are a diverse group of eukaryotes more closely related to animals than other eukaryotes. Fungal cell walls comprise chitin, a polysaccharide that provides structural strength, and glucans, which contribute to flexibility and integrity. Other polysaccharides, such as mannans and galactosans, may supplement or replace chitin in some fungi. These adaptations, along with their preference for acidic environments and tolerance for high osmotic pressure, enable fungi to thrive in various...

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Determination of Biofilm Initiation on Virus-infected Cells by Bacteria and Fungi
12:33

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Published on: July 6, 2016

Pseudohypha budding patterns of Candida albicans.

Verónica Veses1, Neil A R Gow

  • 1The Aberdeen Fungal Group, School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.

Medical Mycology
|April 7, 2009
PubMed
Summary
This summary is machine-generated.

Candida albicans pseudohyphal growth shows unique cell division patterns. Live imaging revealed deviations from typical unipolar budding, expanding the fungus's known morphological diversity.

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Area of Science:

  • Microbiology
  • Mycology
  • Cell Biology

Background:

  • Pseudohyphal growth is a distinct morphological form of Candida albicans, differing from its yeast and true hyphal states.
  • In Saccharomyces cerevisiae, pseudohyphal growth involves modified bipolar budding into synchronous unipolar cell divisions.

Purpose of the Study:

  • To investigate the cell division patterns during pseudohyphal growth in Candida albicans.
  • To compare the observed division patterns with those typically seen in Saccharomyces cerevisiae.

Main Methods:

  • Utilized live cell imaging techniques to observe pseudohyphal development in Candida albicans.
  • Analyzed budding events and cell division patterns in real-time.

Main Results:

  • Candida albicans pseudohyphae exhibit unipolar cell divisions, consistent with previous understanding.
  • Deviations from the unipolar pattern were observed, including bipolar or axial budding events.
  • Buds were occasionally formed from proximal or distal ends of parent pseudohyphae, indicating flexibility in division.

Conclusions:

  • The cell division patterns in Candida albicans pseudohyphae are more complex than previously recognized.
  • These findings expand the known morphological repertoire of cell division in this pathogenic fungus.
  • Understanding these variations may offer new insights into Candida albicans pathogenesis.