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Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
Published on: February 16, 2018
Catalysts based on amino acids for asymmetric reactions in water
Joanna Paradowska1, Maciej Stodulski, Jacek Mlynarski
1Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.
Abstract:
Asymmetric organometallic and organocatalytic processes in aqueous systems are currently of great interest. A few years ago, only a few practitioners studied the subject; now organic reactions in water have become one of the most exciting research areas. The quest to identify water-compatible catalysts has evoked an intense search for new possibilities. Following nature's lead, the application of amino acids as sources of chiral information seems particularly promising for aqueous systems. Herein we provide an overview of very recent advances in the area of asymmetric catalysis in water with amino acids and their derivatives as effective catalysts or essential components of catalysts.
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