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Updated: Jun 24, 2026
11:17
Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin
Published on: March 10, 2021
De novo design of a beta alpha beta motif
Huanhuan Liang1, Hao Chen, Keqiang Fan
1College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
Angewandte Chemie (International Ed. in English)
|April 7, 2009
Abstract:
A designer monomeric protein with a beta alpha beta fold--two parallel beta strands connected by an alpha helix (see structure)--was constructed solely from coded amino acids. The high thermal stability of the structure is due to a large extent to tryptophan-tryptophan interactions between the two beta strands.
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