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Related Experiment Video

Updated: Jun 24, 2026

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies

Published on: January 3, 2011

Corneal topographer based on the Hartmann test.

Yobani Mejía¹, Janneth C Galeano

¹Universidad Nacional de Colombia, Departamento de Física, Ciudad Universitaria, Bogotá D.C., Colombia. ymejiab@unal.edu.co

Optometry and Vision Science : Official Publication of the American Academy of Optometry

|April 7, 2009

Summary

A new Hartmann Test topographer (HT topographer) prototype demonstrates effective performance for analyzing convex surfaces. This innovative device accurately reconstructs corneal topography, potentially improving visualization of defects.

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Area of Science:

Optics
Biomedical Engineering
Ophthalmology

Background:

Accurate measurement of convex surfaces is crucial in optics and ophthalmology.
Existing topographic methods may face limitations like the skew ray problem.
Development of novel topographic devices is essential for improved diagnostic capabilities.

Purpose of the Study:

To evaluate the performance of a prototype Hartmann Test topographer (HT topographer).
To assess the device's suitability for analyzing convex surfaces with an F/# of approximately 1.
To demonstrate the HT topographer's capability in reconstructing surface topography.

Main Methods:

Utilizing Fourier analysis and optical aberration theory on Hartmann patterns.
Obtaining surface sagitta (elevation maps) from Hartmann patterns.

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Last Updated: Jun 24, 2026

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies

Published on: January 3, 2011

Calculating meridional curvature maps through radial derivatives of the sagitta.

Main Results:

The HT topographer successfully measured toric, aspherical, and human corneal surfaces.
Generated elevation and meridional curvature maps were comparable to those from a Placido ring topographer (Tomey TMS-4).
The device showed potential in reconstructing detailed surface topography.

Conclusions:

The HT topographer is capable of reconstructing corneal topography.
The method shows potential for overcoming the skew ray problem, enhancing defect visualization.
Elevation and meridional curvature maps provide valuable topographic data.