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Updated: Jun 24, 2026

Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry
Published on: March 7, 2019
[Amyloid disease in a 93-year-old patient]
Abstract:
Under the term amyloidosis is meant a group of diseases with a variety of clinical symptoms characterized by extracellular deposition of insoluble pathologic fibrillar proteins in tissues and organs. A report is presented of a 93-year-old patient admitted to a multifield hospital for the treatment of cerebral vascular disorders and peripheral nervous disturbances; the patient developed signs of myocardial infarction recognized in clinical/instrumental studies and died. Primary amyloidosis with diffuse vascular lesions in internal organs was diagnosed at autopsy. The death was caused by marked dystrophic changes in myocardium, liver and kidneys, hepatic and renal insufficiency.
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