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Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Gene Therapy00:59

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...

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Related Experiment Video

Updated: Jun 24, 2026

Tracheotomy: A Method for Transplantation of Stem Cells to the Lung
03:45

Tracheotomy: A Method for Transplantation of Stem Cells to the Lung

Published on: February 25, 2007

Cell therapy approaches for lung diseases: current status.

Viranuj Sueblinvong1, Daniel J Weiss

  • 1Division of Pulmonary, Critical Care and Allergy, Department of Medicine, Emory University, Atlanta, GA, USA. vsuebli@emory.edu

Current Opinion in Pharmacology
|April 8, 2009
PubMed
Summary

Stem cell therapy, particularly using mesenchymal stem cells (MSCs), shows promise for lung repair and regeneration. These cells can modulate inflammation and immune responses, offering potential treatments for various lung diseases.

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Tracheotomy: A Method for Transplantation of Stem Cells to the Lung
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Pre-Conditioning the Airways of Mice with Bleomycin Increases the Efficiency of Orthotopic Lung Cancer Cell Engraftment
09:02

Pre-Conditioning the Airways of Mice with Bleomycin Increases the Efficiency of Orthotopic Lung Cancer Cell Engraftment

Published on: June 28, 2018

Area of Science:

  • Regenerative Medicine
  • Pulmonology
  • Cell Biology

Background:

  • Stem cells from embryonic and adult tissues are explored for lung repair.
  • Mesenchymal stem cells (MSCs) show potential in modulating lung inflammation and immune responses.
  • Previous studies indicate safety and efficacy of MSCs in other conditions.

Purpose of the Study:

  • To review recent advances in stem cell therapy for lung diseases.
  • To focus on the role of mesenchymal stem cells (MSCs) in lung development and repair.
  • To highlight the therapeutic potential of stem cells in treating lung conditions.

Main Methods:

  • Review of recent scientific literature and clinical trial data.
  • Analysis of studies on stem cell engraftment and immunomodulation in lung models.
  • Examination of clinical trial outcomes for MSCs in various lung diseases.

Main Results:

  • Mesenchymal stem cells (MSCs) demonstrate immunomodulatory effects in preclinical lung disease models.
  • Clinical trials suggest potential benefits of MSCs in chronic obstructive pulmonary disease.
  • Autologous stem cell administration shows promise for pulmonary hypertension treatment.

Conclusions:

  • Stem cell therapy, especially with MSCs, is a promising approach for lung regeneration and treating lung diseases.
  • MSCs offer therapeutic potential through immunomodulation and repair mechanisms.
  • Ongoing research and clinical trials are crucial for advancing stem cell-based lung therapies.