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Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

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Cancer Vaccines

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Related Experiment Video

Updated: Jun 24, 2026

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Published on: February 12, 2017

Immunotherapy for lung cancer.

Edward A Hirschowitz¹, John R Yannelli

¹Department of Internal Medicine, University of Kentucky, Chandler Medical Center, Lexington, KY, USA. eahirs2@uky.edu

Proceedings of the American Thoracic Society

|April 8, 2009

Summary

Immunotherapy shows promise for lung cancer treatment by inducing specific immune responses. Ongoing trials and vaccine development suggest therapeutic potential for various stages of lung cancer.

Area of Science:

Oncology
Immunology

Background:

Immunotherapy offers high specificity and minimal impact on normal tissues for treating disseminated disease.
Inducing antigen-specific immune responses in lung cancer patients is supported by early-phase clinical trials.

Purpose of the Study:

To review fundamental concepts of cancer immunotherapy.
To provide insights into the development of cancer vaccines.
To update on the status of clinical trials for lung cancer immunotherapy.

Main Methods:

Review of existing literature on immunotherapy for lung cancer.
Analysis of early-phase clinical trial data.
Perspective on vaccine development strategies.

Main Results:

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Published on: January 19, 2019

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Last Updated: Jun 24, 2026

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Published on: February 12, 2017

Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression

Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression

Published on: January 19, 2019

Immunotherapy is a conceptually attractive approach for lung cancer.
Early-phase trials demonstrate the ability to induce antigen-specific immune responses.
Randomized phase IIB studies indicate therapeutic promise for both early- and late-stage lung cancer.

Conclusions:

While not a universal cure, immunotherapy holds significant therapeutic promise for lung cancer.
Further research and clinical trials are essential to optimize immunotherapeutic strategies.
Vaccine development and ongoing trials are crucial for advancing lung cancer treatment.