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Related Concept Videos

Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Fetal Circulation01:14

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Meiosis vs. Mitosis02:57

Meiosis vs. Mitosis

Cell division is necessary for growth and reproduction in organisms. Mitosis aids cell growth and development by dividing somatic cells. In contrast, meiosis causes the division of germ cells and plays an essential role in sexual reproduction. Due to their unique functional requirements, mitosis and meiosis differ from each other in multiple aspects.
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...

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Related Experiment Video

Updated: Jun 24, 2026

Murine Fetal Echocardiography
08:04

Murine Fetal Echocardiography

Published on: February 15, 2013

Fetal pathology in second-trimester miscarriages.

József Gábor Joó1, Artúr Beke, Eniko Berkes

  • 1First Department of Obstetrics and Gynaecology, Faculty of General Medicine, Semmelweis University, Budapest, Hungary. joogabor@hotmail.com

Fetal Diagnosis and Therapy
|April 8, 2009
PubMed
Summary
This summary is machine-generated.

Second-trimester miscarriages are often linked to fetal malformations, particularly single umbilical artery. These miscarriages occur earlier and are more common in male fetuses when malformations are present.

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Area of Science:

  • Reproductive Medicine
  • Fetal Pathology
  • Genetics

Background:

  • Second-trimester miscarriages represent a significant obstetric complication.
  • Understanding the characteristics of these miscarriages is crucial for improving reproductive outcomes.

Purpose of the Study:

  • To analyze the primary characteristics of second-trimester miscarriages using autopsy findings.
  • To identify the prevalence and types of fetal malformations associated with these pregnancy losses.

Main Methods:

  • Retrospective analysis of fetopathological investigation results.
  • Inclusion of 544 aborted fetuses from 486 second-trimester miscarriages.

Main Results:

  • Fetal malformations were identified in 13.05% of cases.
  • Single umbilical artery was the most common isolated malformation (22.4%).
  • Male fetuses showed a dominance in cases with malformations; chromosome aberrations occurred in 1.3%.

Conclusions:

  • Malformation-associated miscarriages occur approximately 3 weeks earlier than those without malformations.
  • Single umbilical artery is a predisposing factor for miscarriage, potentially linked to chromosomal aberrations when combined with other malformations.