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Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

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Charles Bonnet syndrome: a review.

Anita P Schadlu¹, Ramin Schadlu, J Banks Shepherd

¹Wills Eye Hospital, Philadelphia, Pennsylvania, USA. anita.g.prasad@gmail.com

Current Opinion in Ophthalmology

|April 8, 2009

Summary

Charles Bonnet syndrome, characterized by visual hallucinations in mentally normal individuals, is increasingly recognized with an aging population. Increased awareness among healthcare providers is crucial for patient reassurance and management.

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Area of Science:

Ophthalmology
Neuroscience
Geriatrics

Background:

The aging global population leads to a rise in low vision cases from conditions like age-related macular degeneration.
Charles Bonnet syndrome (CBS) involves visual hallucinations in individuals with vision loss but normal mental status.
CBS is underdiagnosed, highlighting a gap in provider awareness.

Purpose of the Study:

To increase awareness of Charles Bonnet syndrome among ophthalmic care providers.
To review the clinical characteristics, causes, and treatment of CBS.
To emphasize the importance of recognizing CBS in elderly patients with low vision.

Main Methods:

Review of clinical descriptions and case reports.
Analysis of theories on the underlying mechanisms of CBS.
Evaluation of current and potential treatment strategies.

Main Results:

CBS presents as formed visual hallucinations due to visual system disturbances in mentally normal patients.
Theories on CBS causes are diverse, offering insights into visual system function.
Incidence varies, but CBS is frequently underdiagnosed; pharmacologic interventions are reported, with reassurance and visual improvement being key.
Patient and caregiver understanding of CBS can significantly reduce patient anxiety.

Conclusions:

Ophthalmologists and physicians caring for elderly or low-vision patients must be aware of CBS.
Recognition and understanding of CBS by healthcare providers are vital for patient care and anxiety reduction.
Further research into effective treatment options for Charles Bonnet syndrome is warranted.