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Tolerability and clinical utility of the Bravo pH capsule in children

Brian E Lacy1, Susan Edwards, Lisa Paquette

  • 1Division of Gastroenterology and Hepatology, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA. brian.lacy@hitchcock.org

Journal of Clinical Gastroenterology
|April 8, 2009
PubMed

Insights

The Bravo pH capsule is safe and well-tolerated for evaluating acid reflux in children. This diagnostic tool significantly impacts clinical management decisions for pediatric patients.

Area of Science:

  • Pediatric Gastroenterology
  • Gastrointestinal Motility Disorders
  • Diagnostic Technologies

Background:

  • Acid reflux is a prevalent condition in pediatric populations.
  • Accurate pH testing is crucial for correlating acid exposure with symptoms.
  • Prospective data on the Bravo pH capsule's utility in children was lacking.

Purpose of the Study:

  • To prospectively assess the tolerability of the Bravo pH capsule in pediatric patients.
  • To evaluate the clinical utility and impact on management of the Bravo pH capsule in children.
  • To determine the safety profile of the Bravo pH capsule in a pediatric cohort.

Main Methods:

  • A prospective, open-label trial was conducted at an academic medical center.
  • Demographics, symptoms, and medication use were recorded for 50 children.
  • Clinical management changes post-Bravo capsule placement were tracked.

Main Results:

  • No complications were reported in the 50 children studied (mean age 13 years).
  • The Bravo pH capsule study results altered clinical management in 88% of children.
  • Management changes were more frequent in children with abnormal pH study results (94%) compared to normal results (78%).

Conclusions:

  • The Bravo pH capsule is a safe and well-tolerated diagnostic tool for pediatric acid reflux evaluation.
  • Data from the Bravo pH capsule frequently leads to changes in patient management.
  • This technology offers significant clinical utility in diagnosing and managing acid reflux in children.
Abstract

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