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Related Concept Videos

Solvents01:12

Solvents

A solvent is a substance, most often a liquid, that can dissolve other substances. Here, the substance being dissolved is called a solute. When a solvent and a solute combine, they form a solution - a homogenous mixture of both the solvent and the solute. Water is a universal biological solvent. Its polar structure allows it to dissolve many other polar compounds. The ability of water to dissolve is governed by a balance between water molecules binding to each other and binding to the solute.
A...
Entropy and Solvation02:05

Entropy and Solvation

The process of surrounding a solute with solvent is called solvation. It involves evenly distributing the solute within the solvent. The rule of thumb for determining a solvent for a given compound is that like dissolves like. A good solvent has molecular characteristics similar to those of the compound to be dissolved. For example, polar solutions dissolve polar solutes, and apolar solvents dissolve apolar solutes. A polar solvent is a solvent that has a high dielectric constant (ϵ ≥ 15); an...

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Related Experiment Video

Updated: Jun 24, 2026

Fabrication of the Thermoplastic Microfluidic Channels
16:00

Fabrication of the Thermoplastic Microfluidic Channels

Published on: February 3, 2008

Surface-directed channels filled with organic solvents.

Masashi Watanabe1

  • 1Faculty of Textile Science and Technology, Shinshu University, 3-15-1 Tokida, Ueda, Nagano 386-8567, Japan. mwatana@giptc.shinshu-u.ac.jp

Lab on a Chip
|April 8, 2009
PubMed
Summary

Novel surface-directed microfluidic channels were developed to handle organic solvents like xylene. This advancement expands the utility of microfluidic devices for applications involving non-aqueous solutions.

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Area of Science:

  • Materials Science
  • Chemical Engineering
  • Microfluidics

Background:

  • Microfluidic devices typically use pipe-like channels.
  • Surface-directed channels, created between patterned glass slides, are an emerging alternative.
  • Existing surface-directed channels primarily accommodate aqueous solutions, limiting their use with organic solvents.

Purpose of the Study:

  • To develop novel surface-directed microfluidic channels capable of containing various organic solvents.
  • To demonstrate the compatibility of these channels with solvents such as xylene, nitrobenzene, and dimethyl sulfoxide.

Main Methods:

  • Chemically patterning flat glass slides.
  • Treating glass slides with (tridecafluoro-1,1,2,2-tetrahydrooctyl)trimethoxysilane.
  • Fabricating surface-directed channels between stacked, treated glass slides.

Main Results:

  • The developed channels successfully contained and directed organic solvents, including xylene, nitrobenzene, and dimethyl sulfoxide.
  • Xylene was continuously flowed through a channel (1 mm wide, 40 mm long, 0.14 mm deep) at high flow rates (up to 99.99 microL min(-1)).

Conclusions:

  • The novel surface-directed channels offer a robust platform for microfluidic applications involving organic solvents.
  • This research expands the scope of microfluidic applications, particularly in organic synthesis and other fields requiring non-aqueous media.