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Updated: Jun 24, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
[Purpura fulminans, cerebral infarcts and multiorganic dysfunction due to hantavirus infection. Review and case
Gustavo R Marín1, Berta Baspineiro, María R Miranda
1Unidad de Nefrología, Hospital de Niños Héctor Quintana, Jujuy, Argentina. tama@imagine.com.ar
Abstract:
Multiorganic failure is a rare manifestation of hantavirus infection but it should be included among differential diagnoses of multiorganic failure in the pediatric age. Currently, there is no effective therapy for this infection. A high suspicion index and early referral to a pediatric intensive care unit with extracorporeal membrane oxygenation may lead to a favourable impact in the outcome. We report a fatal case of hantavirus infection in a 9-year-old girl with a severe disease refractory to hemodynamic supportive measures, and characterized by purpura fulminans, cerebral infarcts, cardiopulmonary failure, and acute renal failure. Commentaries and review about these infrequent clinical manifestations are made.
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