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Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Technical note: prediction of sex based on five skull traits using decision analysis (CHAID)
Joan C Stevenson1, Eldon R Mahoney, Phillip L Walker
1Department of Anthropology, Western Washington University, 1305 E Victor St, Bellingham, Washington 98225, USA. joan.stevenson@wwu.edu
Chi-square automatic interaction detection (CHAID) offers improved sex determination from skeletal remains compared to logistic regression. CHAID effectively identifies interactions among traits, particularly in English and European American samples.
Area of Science:
- Forensic Anthropology
- Biological Anthropology
- Bioinformatics
Background:
- Osteologists traditionally assess skeletal sex using subjective ordinal scores of dimorphic traits.
- Logistic regression (LR) models have been developed for probabilistic sex determination but often neglect trait interactions.
Purpose of the Study:
- To evaluate Chi-square automatic interaction detection (CHAID) as an alternative classification strategy for skeletal sex determination.
- To analyze the predictive accuracy of trait combinations using CHAID, focusing on interactions.
- To compare CHAID performance against logistic regression using known-sex skeletal samples.
Main Methods:
- CHAID decision trees were employed to analyze 31 combinations of five sexually dimorphic skull traits.
- Known-sex samples (n=304) of English, African American, and European American ancestry were utilized.
- Selection criteria for optimal sex predictive trait combinations (SPTCs) included >=75% accuracy for both sexes and <5% sex bias.
Main Results:
- CHAID produced suitable SPTCs for English and European American samples, but not for the African American sample.
- Out-of-sample testing indicated that trees derived from the English and combined (all groups) samples exhibited the best predictive performance.
- CHAID's focus on variable interactions offers a potentially more robust approach to sex determination.
Conclusions:
- CHAID is a valuable tool for skeletal sex determination, especially when trait interactions are significant.
- The effectiveness of CHAID models may vary across different ancestral populations.
- Further research is warranted to refine CHAID applications for diverse forensic and archaeological contexts.
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