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Laboratory Scale Production and Purification of a Therapeutic Antibody
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Laboratory Scale Production and Purification of a Therapeutic Antibody

Published on: January 24, 2017

Development trends for therapeutic antibody fragments

Aaron L Nelson1, Janice M Reichert

  • 1Tufts University School of Medicine, Boston, MA, USA.

Nature Biotechnology
|April 9, 2009
PubMed
Summary

No abstract available in PubMed .

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Hybridoma Technology01:31

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Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
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