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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
Published on: November 7, 2025
Imaging techniques for prostate cancer: implications for focal therapy
Baris Turkbey1, Peter A Pinto, Peter L Choyke
1National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1088, USA.
Nature Reviews. Urology
|April 9, 2009
Summary
Focal therapy for prostate cancer offers a less invasive option for localized disease. Accurate imaging is crucial for the success of this approach, guiding diagnosis, staging, and treatment monitoring.
Area of Science:
- Oncology
- Radiology
- Medical Imaging
Background:
- Prostate cancer's multifocal nature historically required whole-gland therapy.
- Increased PSA screening leads to earlier detection of less-advanced prostate cancer.
- Patients increasingly seek to avoid adverse effects associated with whole-gland treatments.
Purpose of the Study:
- To review conventional and novel prostate imaging techniques for localized prostate cancer.
- To evaluate the role of advanced imaging in enabling focal therapy for prostate cancer.
- To discuss the potential of image-guided biopsy and focal therapy.
Main Methods:
- Review of existing literature on prostate imaging modalities.
- Analysis of advancements in Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) for prostate cancer.
- Discussion of conventional imaging versus new targeted imaging developments.
Main Results:
- Conventional imaging methods have limitations in accurately characterizing prostate cancer.
- Developments in MRI and PET offer improved precision for prostate imaging.
- Targeted imaging holds promise for enhancing the accuracy of focal therapy.
Conclusions:
- Focal therapy is a viable option for localized prostate cancer, contingent on accurate imaging.
- Advanced imaging techniques are essential for precise diagnosis, staging, and treatment monitoring.
- Image-guided biopsy and focal therapy represent a promising future direction in prostate cancer management.

