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Updated: Jun 24, 2026
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Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Di-platinum complexes containing thiolato-urea ligands: structural and anion binding studies
Carolina Mendoza1, Jordi Benet-Buchholz, Miquel A Pericás
1Institute of Chemical Research of Catalonia (ICIQ), Avgda. Països Catalans16, 43007, Tarragona, Spain.
Dalton Transactions (Cambridge, England : 2003)
|April 9, 2009
Summary
New platinum complexes act as selective receptors for inorganic phosphate, utilizing urea groups for hydrogen bonding. An unusual 1D coordination polymer featuring platinum and lead was also synthesized and characterized.
Area of Science:
- Coordination Chemistry
- Supramolecular Chemistry
- Materials Science
Background:
- Platinum complexes are investigated for their unique chemical properties.
- Thiolato-bridged complexes offer potential for anion recognition.
- Urea functionalities can participate in hydrogen bonding interactions.
Purpose of the Study:
- To synthesize and characterize novel di-platinum(II) thiolato-bridged complexes.
- To investigate the anion binding capabilities of these complexes, particularly their selectivity.
- To explore the formation and structure of coordination polymers involving these platinum complexes.
Main Methods:
- Synthesis of di-platinum(II) thiolato-bridged complexes.
- X-ray crystallography for structural determination.
- (1)H NMR spectroscopy and indicator displacement assays for anion binding studies.
Main Results:
- Successful synthesis and structural confirmation of di-platinum(II) thiolato-bridged complexes.
- Demonstrated hydrogen bonding interactions of urea groups with anions.
- Quantitative and qualitative evidence of selective binding of inorganic phosphate.
- Isolation and structural characterization of a novel 1D coordination polymer containing platinum and lead.
Conclusions:
- The synthesized platinum complexes effectively act as receptors for anions through hydrogen bonding.
- These receptors exhibit high selectivity for inorganic phosphate.
- A novel 1D coordination polymer with a unique structure was successfully synthesized and characterized.
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