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In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
Published on: January 20, 2019
Azurophilic inclusions in plasma cells
1Department of Pathology & Microbiology, Section of Haematology, The Aga Khan University Hospital, PO Box 3500, Stadium Road, Karachi 74800, Pakistan. natasha.ali@aku.edu
Abstract:
We report a 45-year-old man with complaints of chest pain and weight loss who was referred for a bone marrow/trephine procedure to the Aga Khan University Hospital. Bone marrow examination showed plasmacytosis of 95% with plasma cells containing coarse Auer rod-like azurophilic inclusions, which failed to stain positively with Sudan Black B or periodic acid Schiff stain. These inclusions have rarely been previously reported as they are more significant morphologically rather than having a prognostic value.
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