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Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration01:25

Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration

Hemoperfusion and hemofiltration are critical techniques in medical treatments to eliminate accumulated drugs, metabolites, and electrolytes from the bloodstream. These methods are particularly vital in cases of accidental poisoning and drug overdose.Hemoperfusion involves passing blood through an adsorbent material to remove unwanted substances. The main adsorbents used in hemoperfusion include activated charcoal and Amberlite resins. Activated charcoal can adsorb both polar and nonpolar...
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Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
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Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in critically...

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Updated: Jun 24, 2026

Novel Protocol for Generating Physiologic Immunogenic Dendritic Cells
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[Extracorporeal photopheresis].

U Just1, R Knobler

  • 1Universitätsklinik für Dermatologie AKH-Wien, Währinger Gürtel 18-20, 1090 Wien, Osterreich. ulrike.just@meduniwien.ac.at

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|April 9, 2009
PubMed
Summary

Photopheresis, initially a dermatological treatment, is now used across many fields. Consulting a dermatologist experienced in photopheresis is crucial, even for non-skin conditions like graft-versus-host disease.

Area of Science:

  • Photomedicine and photobiology are foundational to dermatology.
  • Photopheresis utilizes light-based therapies.

Context:

  • Photopheresis originated in dermatology.
  • Its application has expanded to diverse medical disciplines.
  • Conditions like graft-versus-host disease and Crohn's disease are treated with photopheresis.

Purpose:

  • To highlight the expanding role of photopheresis beyond dermatology.
  • To emphasize the necessity of dermatological expertise in photopheresis application.

Summary:

  • Photopheresis, initially developed for dermatological conditions, is now a recognized treatment in various medical fields.
  • Despite its broader use, an experienced dermatologist should oversee its application, even for non-dermatological indications.
  • This includes conditions such as graft-versus-host disease and Crohn's disease.

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An In Vitro Approach to Photodynamic Therapy
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Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ
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An In Vitro Approach to Photodynamic Therapy
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An In Vitro Approach to Photodynamic Therapy

Published on: August 17, 2018

Impact:

  • Ensures appropriate and effective use of photopheresis across disciplines.
  • Reinforces the importance of specialized dermatological knowledge in photomedicine.
  • Facilitates better patient outcomes through expert-guided photopheresis treatment.