Reversible acute cognitive dysfunction induced by bilateral STN stimulation

Deep brain stimulation of the subthalamic nucleus (STN) is an effective treatment modality for motor symptoms of advanced Parkinson's disease. Recent studies focus on exploring its possible effects on cognition and behavior. We present a case with acute cognitive dysfunction due to misalignment of the electrodes to the ventromedial STN which persisted for 3 weeks but was totally reversed by proper repositioning to the dorsolateral STN.