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Multicomponent reactions of cyclobutanones

Michael C Pirrung1, Jianmei Wang

  • 1Department of Chemistry, University of California, Riverside, California 92521-0403, USA. michael.pirrung@ucr.edu

The Journal of Organic Chemistry
|April 10, 2009
PubMed
Summary

Cyclobutanones are now known reactants in multicomponent reactions like the Ugi and Passerini reactions. Conducting these reactions in water significantly enhances their efficiency, leading to novel applications such as aspartame analogue synthesis.

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