Species differences in metabolism and pharmacokinetics: are we close to an understanding?

Female meadow voles housed in long and short daylengths respond to exogenous estrogen with similar mating latencies.

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Hemispheric specialization in emotion: attention, arousal, and EEG activation in unilateral temporal lobe epilepsy.

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Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil.

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Lipophilicity in PK design: methyl, ethyl, futile.

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SAR and mechanistic pathways of oxadiazole derivatives: targeting enzymes for antidiabetic therapy.

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Humanized mouse models for drug metabolism and drug transport: a systematic review.

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Flexible use of conserved motifs constrains genome access in cell type evolution.

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The distribution of fitness effects of nonsynonymous mutations varies phylogenetically across animals.

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FEMS microbiology ecology·2026

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Species differences in metabolism and pharmacokinetics: are we close to an understanding?

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Female meadow voles housed in long and short daylengths respond to exogenous estrogen with similar mating latencies.

Hemispheric specialization in emotion: attention, arousal, and EEG activation in unilateral temporal lobe epilepsy.

Smads mediate signaling of the TGFbeta superfamily in normal keratinocytes but are lost during skin chemical carcinogenesis.

Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil.

Lipophilicity in PK design: methyl, ethyl, futile.

Evidence for charge domains on developing enamel crystal surfaces.

Reprogramming of Hepatic Drug Metabolism following Early-life Xenobiotic Exposure: Insights from Nuclear Receptor Pathways.

Metabolic pharmacology of anthelmintic drugs targeting mitochondrial fumarate reductase in neurocysticercosis.

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SAR and mechanistic pathways of oxadiazole derivatives: targeting enzymes for antidiabetic therapy.

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Humanized mouse models for drug metabolism and drug transport: a systematic review.

Flexible use of conserved motifs constrains genome access in cell type evolution.

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Osteology, variation, and adaptations of the oldest Eurasian little owl Athene vallgornerensis, with implications for the evolutionary history of the genus Athene (Aves: Strigidae).

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