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Prion protein peptides as vaccines

M Ghielmetti1, T Vranac, V Curin Serbec

  • 1Department for the Production of Diagnostic Reagents and Research, Blood Transfusion Centre of Slovenia, Slajmerjeva 6, 1000 Ljubljana, Slovenia.

Mini Reviews in Medicinal Chemistry
|April 10, 2009
PubMed

Investigations into the immunogenicity of the prion protein are ongoing. To combat its pathological isoform without affecting the cellular protein is a challenge in prion research. We here summarize the studies in which prion protein peptides have been used for immunization, to thus determine the most immunogenic parts of the prion protein.

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