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Published on: June 6, 2020
Effect of cesarean delivery on the endometrium
Jara Ben-Nagi1, Amy Walker, Davor Jurkovic
1Early Pregnancy and Gynaecology Assessment Unit, King's College Hospital, London, UK. jbennagi@gmail.com
Objective:
To compare endometrial tissue samples from cesarean scar (CS) sites and from the posterior uterine wall to better understand the pathophysiology of implantation into a CS.
Methods:
Endometrial samples were taken from both a CS site and the posterior wall in premenopausal women with CSs, and from the posterior wall in premenopausal women who had spontaneous vaginal deliveries (SVDs) only.
Results:
In the secretory phase, there were significantly fewer leukocytes at CS sites than in the endometrium of women who had SVDs only (P<0.05). Significant differences in leukocytic infiltration and cell proliferation between the proliferative and secretory phases were only found in women who had SVDs only (P<0.05).
Conclusion:
Leukocyte recruitment to the endometrium during the secretory phase may be affected by the presence of a CS.
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