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Updated: Jun 24, 2026
07:35
Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
Published on: June 8, 2020
[Colorectal cancer in a population with a guaiac-based screening programme]
Matilde Navarro1, Mercè Peris, Gemma Binefa
1Servicio de Prevención y Control del Cáncer, Institut Català d'Oncologia, L'Hospitalet de Llobregat, Barcelona, España. mnavarrogarcia@iconcologia.net
Medicina Clinica
|April 10, 2009
Summary
Colorectal cancer (CRC) screening in L'Hospitalet significantly benefits participants, detecting cancers earlier and before symptoms arise. This population-based program demonstrates effective CRC detection and improved patient outcomes.
Area of Science:
- Oncology
- Public Health
- Epidemiology
Context:
- Colorectal cancer (CRC) screening effectiveness is contingent upon implementation and adherence.
- A population-based CRC screening program was initiated in L'Hospitalet, Spain, in 2000.
- Understanding the characteristics of CRC cases detected by screening is crucial for evaluating program impact.
Purpose:
- To determine the number of CRC cases diagnosed in L'Hospitalet.
- To identify features of CRC cases detected by the population-based screening program.
- To compare CRC cases detected via screening versus clinical diagnosis.
Summary:
- 510 CRC cases were diagnosed; 88% were invited to the screening program.
- CRC detected by screening (12.9% of cases) presented with earlier stages (0-II: 75.9%) and fewer symptoms compared to clinically diagnosed cases.
- Non-participants (78.0%) had a higher proportion of advanced stage (III-IV: 54.2%) and symptomatic cancers.
Impact:
- Population-based screening programs are beneficial for early CRC detection.
- Screening facilitates diagnosis of CRC before symptom onset.
- Early-stage detection through screening improves prognosis and treatment outcomes.
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