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Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Papillary Dermis

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...

Reticular Dermis

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...

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Dermatofibrosarcoma protuberans.

R De Pasquale¹, F Dinotta, L Scuderi

¹Dermatologic Clinic, University of Catania, Catania, Italy. cldermct@nti.it

Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Societa Italiana Di Dermatologia E Sifilografia

|April 10, 2009

Summary

This summary is machine-generated.

Dermatofibrosarcoma protuberans (DFSP) is a rare skin cancer. This case highlights an unusual presentation of DFSP in a woman, emphasizing the need for accurate diagnosis.

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Area of Science:

Dermatology
Oncology
Pathology

Background:

Dermatofibrosarcoma protuberans (DFSP) is an uncommon, locally aggressive skin tumor.
It typically affects young adult men on the trunk and extremities.
DFSP originates in the dermis and can invade deeper tissues, with rare metastasis.

Observation:

A 54-year-old woman presented with an asymptomatic, red-violaceous plaque on her left submammary area.
The lesion featured sharply defined borders and two distinct outgrowths.
One outgrowth was smooth and flesh-colored, the other reddish with a cobblestone texture.

Findings:

Histological and immunohistochemical analyses confirmed the diagnosis of DFSP.
The case presented an atypical clinical appearance for DFSP.
This presentation underscores the diverse clinical manifestations of DFSP.

Implications:

Accurate diagnosis of DFSP is crucial, even with unusual presentations.
Understanding varied DFSP appearances aids in early detection and treatment.
Further research into DFSP etiology and presentation is warranted.