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Hand osteoarthritis in Chuvashian population: prevalence and determinants
Leonid Kalichman1, Eugene Kobyliansky
1Department of Physical Therapy, Faculty of Health Sciences, Recanati School for Community Health Professions, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel. kalihman@zahav.net.il
Insights
Radiographic hand osteoarthritis (OA) is highly prevalent in older Chuvashians, particularly women with obesity. Moderate alcohol intake may offer a protective effect for women
Area of Science:
- Rheumatology
- Epidemiology
- Public Health
Background:
- Hand osteoarthritis (OA) is a common degenerative joint disease.
- Understanding its prevalence and risk factors in diverse populations is crucial for public health initiatives.
Purpose of the Study:
- To determine the prevalence of radiographic hand OA in a Chuvashian community sample.
- To investigate associations between hand OA and age, sex, body mass index (BMI), smoking, and alcohol consumption.
Main Methods:
- A community-based sample of 443 males and 384 females from the Chuvashian population was studied.
- Radiographic evaluation of 14 hand joints per individual using the Kellgren and Lawrence grading scheme.
- Statistical analyses included prevalence estimation, regression models, and chi-squared tests.
Main Results:
- High prevalence of hand OA observed, with 89.2% of males and 97.6% of females over 65 years having at least one affected joint.
- Obesity was associated with a nearly threefold increased risk of hand OA in females, but not in males.
- No significant association was found between smoking and hand OA prevalence.
- Moderate alcohol consumption demonstrated a protective effect on hand OA prevalence in women.
Conclusions:
- Age is a significant factor in hand OA prevalence in the Chuvashian population.
- Obesity is a key risk factor for hand OA in women, highlighting potential sex-specific differences in disease etiology.
- Moderate alcohol consumption may have a protective role against hand OA in women, warranting further investigation.
Abstract:
The objectives of this study are to evaluate the prevalence of radiographic hand osteoarthritis (OA) in Chuvashian community-based sample and its associations with age, sex, body mass index (BMI), smoking, and alcohol consumption. The study population was comprised of Chuvashians (443 males, age 47.4 ± 17.0 years and 384 females, age 50.8 ± 16.3 years). OA was evaluated for 14 joints of each hand according to the Kellgren and Lawrence grading scheme. Statistical analyses included prevalence estimation, linear, logistic and polynomial regressions, and χ2 tests. After the age of 65 years, 89.2% of males and 97.6% of females had at least one affected joint. For males and females the best-fitted and most parsimonious model of association between age and number of affected hand joints was the two interval linear one. After adjustment for age, no association between prevalence of hand OA and BMI was found in males. However, females with obesity have almost three times higher risk of development of hand OA than those with normal weight. No association was found between smoking and prevalence of hand OA. Moderate alcohol consumption showed protective effect on prevalence of hand OA in women.
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