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Updated: Jun 24, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
IgE-mediated fungal allergy in allergic fungal sinusitis
Harshita Pant1, Mark A Schembri, Peter J Wormald
1Department of Otorhinolaryngology Head and Neck Surgery, the University of Adelaide, Adelaide, Australia. panth@upmc.edu
Abstract:
This review will address the current knowledge of the pathogenic mechanisms in allergic fungal sinusitis (AFS) and the basis for the current classification of a subgroup of chronic rhinosinusitis patients. Special attention is directed to the role of immunoglobulin E (IgE)-mediated fungal allergy in the pathogenesis of AFS. Concepts relating to the mucosal inflammatory response are introduced, as a knowledge of the reactions of the sinus mucosal cells can lead to a better understanding of the mechanisms perpetuating and maintaining the chronic inflammation. Laryngoscope, 2009.
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