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Unusual casts in a case of multiple myeloma

Sanjeev Sethi1, Matthew H Hanna, Fernando C Fervenza

  • 1Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA. sethi.sanjeev@mayo.edu

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
|April 11, 2009
PubMed
Abstract

No abstract available in PubMed .

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...