Diastereoselective Ritter reactions of chiral secondary benzylic alcohols
Philipp Rubenbauer1, Thorsten Bach
1Lehrstuhl für Organische Chemie 1, Technische Universität München, 85747 Garching, Germany.
Chemical Communications (Cambridge, England)
|April 11, 2009
Abstract:
An acid-catalysed Ritter reaction of chiral secondary benzylic alcohols enables diastereoselective access to chiral amides, which represent inter alia valuable intermediates for the synthesis of chiral 1,2-diamines and beta-amino acids.
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