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Histopathology of canine sporotrichosis: a morphological study of 86 cases from Rio de Janeiro (2001-2007)

L H M de Miranda1, L P Quintella, I B dos Santos

  • 1Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil. luisahmiranda@gmail.com

Mycopathologia
|April 11, 2009
PubMed

Insights

Histopathological analysis of canine sporotrichosis skin lesions revealed suppurative granulomatous inflammation in most cases. Fungus-specific staining identified Sporothrix schenckii in some lesions, highlighting the need for careful diagnostic interpretation.

Area of Science:

  • Veterinary Pathology
  • Mycology

Background:

  • Sporotrichosis is a fungal infection affecting animals and humans.
  • Histopathological examination is crucial for diagnosing skin lesions in dogs.

Purpose of the Study:

  • To describe the histopathological findings in canine skin lesions suspected of sporotrichosis.
  • To evaluate the efficacy of fungus-specific staining for identifying Sporothrix schenckii.

Main Methods:

  • Histopathological examination of 86 canine skin lesions.
  • Fungus-specific staining on serial sections of selected lesions.

Main Results:

  • Suppurative granulomatous inflammation was the predominant finding (88.37%).
  • Plasma cells and peripheral inflammatory infiltrates were common.
  • Sporothrix schenckii yeast cells were identified in 36 cases (41.86%), exclusively in suppurative granulomatous lesions.

Conclusions:

  • Histopathology is essential for diagnosing canine sporotrichosis.
  • Fungus-specific staining aids in identifying Sporothrix schenckii, particularly in suppurative granulomatous inflammation.
  • Negative staining results do not exclude sporotrichosis, especially in endemic areas; epidemiological data is vital.

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