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Gastric outlet obstruction by Brunner's gland hyperplasia in an 8-year-old child
Ikbel El Faleh1, Nicolas Lutz, Maria-Chiara Osterheld
1Department of Gastroenterology and Clinical Nutrition, University Hospital Lausanne, 1011 Lausanne, Switzerland.
Insights
Brunner's gland hyperplasia is rare in children, causing gastric outlet obstruction. This report details the youngest case, emphasizing histopathology and treatment options for this rare pediatric condition.
Area of Science:
- Gastroenterology
- Pediatric Surgery
- Surgical Pathology
Background:
- Brunner's gland hyperplasia (BGH) is a rare duodenal submucosal gland condition.
- While documented in adults causing bleeding or obstruction, pediatric cases are exceptionally rare, with only two prior reports linked to chronic renal failure.
Observation:
- This study presents the third pediatric case and the youngest reported instance of gastric outlet obstruction attributed to BGH.
- The case highlights the critical need to consider BGH in pediatric patients presenting with upper gastrointestinal obstruction.
Findings:
- Histopathological examination confirmed BGH as the cause of obstruction.
- The report focuses on the specific histopathologic features and discusses available treatment strategies.
Implications:
- This case expands the understanding of BGH in the pediatric population, particularly its association with gastric outlet obstruction.
- It underscores the importance of accurate diagnosis and tailored treatment for BGH in young patients, even in the absence of chronic renal failure.
Abstract:
Several cases of Brunner's gland hyperplasia causing hemorrhage, obstruction, or intussusception have been published in the adult literature. Similar cases in the pediatric population are very rare and have only been described twice, always associated with chronic renal failure. We report the third and youngest case of gastric outlet obstruction because of Brunner's gland hyperplasia focusing on histopathologic condition and treatment based on a review of the literature.
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