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Updated: Jun 24, 2026

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Human Blastocyst Biopsy and Vitrification
Published on: July 26, 2019
Different embryonic development after blastomere biopsy for preimplantation genetic diagnosis, observed by time-lapse
Yukihiro Terada1, Tomohisa Ugajin1, Hisataka Hasegawa1
1Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai, Japan.
Fertility and Sterility
|April 14, 2009
Abstract:
Using time-lapse imaging, we found different behavior of mouse embryonal development after blastomere biopsy for preimplantation genetic diagnosis. Blastomere removal has effects on the developmental behavior of the mouse embryo, including speed of growth, contraction and expansion movements, and hatching.

