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Updated: Jun 24, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
Total knee arthroplasty failure and gouty arthropathy
Michael T Freehill1, Edward F McCarthy, Harpal S Khanuja
1Department of Orthopedic Surgery, The Johns Hopkins University, Baltimore, MD 21224-2780, USA.
Abstract:
We present a patient with gout and a total knee arthroplasty that failed secondary to infection. The English literature records only 5 other cases of gouty attacks after total knee arthroplasty. Symptoms, presentation, and laboratory tests do not definitively differentiate between infection and gout, but crystals in the joint aspirate are diagnostic. This case stresses the importance of recognizing crystalline arthropathy as a source of a painful knee and as a complicating factor during revision surgery.