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Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors
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Encapsulation and quantification of multiple dye guests in unmodified poly(amidoamine) dendrimers as a function of

Katrina K Kline1, Elizabeth J Morgan, Lisa K Norton

  • 1Department of Chemistry, University of Missouri, 125 Chemistry Bldg., Columbia, MO 65211, USA.

Talanta
|April 14, 2009
PubMed

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Aryldiazonium Salts to Azo Dyes: Diazo Coupling01:11

Aryldiazonium Salts to Azo Dyes: Diazo Coupling

The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the para position.