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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Ulnar artery vasculopathy in systemic sclerosis
Jeong Ha Park1, Yoon-Kyoung Sung, Sang-Cheol Bae
1Department of Rheumatology, The Hospital for Rheumatic Diseases, Hanyang University, Seoul, Republic of Korea.
Insights
Systemic sclerosis patients with digital ulcers often have ulnar artery issues. Early screening and revascularization are recommended for severe cases, especially with diffuse sclerosis.
Area of Science:
- Vascular Medicine
- Rheumatology
- Radiology
Background:
- Digital ulceration is common in systemic sclerosis (SSc).
- Macrovascular involvement in SSc is increasingly recognized.
- Limited data exists on macrovascular disease in SSc patients with digital ulcers.
Purpose of the Study:
- To investigate the prevalence and characteristics of macrovascular involvement, specifically ulnar artery disease, in SSc patients with Raynaud's phenomenon and digital ulceration.
- To assess the need for early surgical intervention in this patient cohort.
Main Methods:
- Retrospective review of medical records and brachial angiographic findings.
- Analysis of 19 SSc patients with Raynaud's phenomenon and digital ulceration.
- Comparison of risk factors between patients with and without ulnar artery involvement.
Main Results:
- Ulnar artery involvement was frequent in the studied SSc patients.
- No significant difference in macrovascular disease risk factors was found between involved and non-involved groups.
- Five out of thirteen surgically treated patients underwent vascular grafting for ulnar artery disease.
Conclusions:
- Ulnar artery involvement is a notable finding in SSc patients with severe Raynaud's phenomenon and digital ulceration.
- Angiographic screening and early revascularization should be considered for these patients, particularly those with diffuse SSc.
Abstract:
Although digital ulceration frequently occurs in patients with systemic sclerosis, there have been few reports on macrovascular involvement. Macrovascular disease in systemic sclerosis has recently been described. We retrospectively reviewed the medical records and brachial angiographic findings of 19 systemic sclerosis patients, who exhibited Raynaud's phenomenon and digital ulceration. We found that ulnar artery involvement is frequent in systemic sclerosis, although the precise mechanism is not known. There was no significant difference in risk factors of macrovascular disease between ulnar artery-involved patients and not-involved subjects. Thirteen patients underwent surgical intervention; five of the 13 patients had vascular graft performed due to ulnar artery involvement. We suggest that angiographic screening and early surgical intervention such as revascularization should be considered in patients with systemic sclerosis who manifest a severe form of Raynaud's phenomenon and/or digital ulceration and especially in patients with diffuse sclerosis.
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