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Updated: Jun 24, 2026
09:35
Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells
Published on: May 19, 2020
[Cutaneous heterotopic meningeal nodules]
Maxime Battistella1, Olivier Verola, Isabelle Moulonguet
1Service de pathologie, hôpital Saint-Louis, AP-HP, 1, avenue Claude-Vellefaux, 75010 Paris, France. maximebattistella@hotmail.com
Annales De Pathologie
|April 15, 2009
Summary
Cutaneous heterotopic meningeal nodules are rare scalp lesions. Progesterone receptor (PR) expression may serve as a novel diagnostic tool for these congenital growths.
Area of Science:
- Dermatology
- Pathology
- Oncology
Background:
- Cutaneous heterotopic meningeal nodules are rare congenital lesions.
- Their pathogenesis is debated, with theories including ectopic arachnoidal cell proliferation or developmental defects.
- These nodules typically present on the scalp or spine in children and young adults.
Observation:
- Histological examination reveals characteristic arachnoidal cells expressing EMA and vimentin.
- These cells infiltrate collagen and form whorls or psammomatous bodies.
- The study observed progesterone receptor (PR) expression in a specific case.
Findings:
- Progesterone receptor (PR) expression was identified in a cutaneous heterotopic meningeal nodule.
- This finding suggests PR expression could be a distinguishing feature.
Implications:
- The expression of progesterone receptor (PR) may offer a new diagnostic marker for cutaneous heterotopic meningeal nodules.
- Further research into PR expression could refine understanding and diagnosis of these rare lesions.
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