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Updated: Jun 24, 2026
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Sarcoidosis and melanoma: a referral center study of 1,199 cases
Pascal Seve1, Anne Marie Schott, Michel Pavic
1Department of Internal Medicine, Hospices civils de Lyon, Université Lyon 1, Lyon, France.
Background:
Case reports and small short case series have described patients with sarcoidosis and melanoma.
Objectives:
To examine the relation between sarcoidosis and melanoma.
Methods:
Computerized search of all patients seen at our department of dermatology between 1998 and 2007 and review of the literature using a Medline search from 1985 to June 2008.
Results:
We identified 7 cases in our population of 1,199 melanoma inpatients. Including these cases, 20 cases of sarcoidosis have been described in melanoma patients. Fifteen patients had their sarcoidosis diagnosed after melanoma. In 7 cases, sarcoidosis was related to immunotherapy. Sarcoidosis presented mainly as pulmonary disease without severe organ involvement, with a benign evolution.
Conclusion:
Our referral center study shows a prevalence of sarcoidosis of 0.58% among melanoma inpatients. Clinicians should be aware of the possibility that sarcoidosis may initially manifest itself in melanoma patients, especially after treatment with immunotherapy, and mimic metastatic disease.
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