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Updated: Feb 10, 2026
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Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
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Familial mediterranean fever and multiple sclerosis--a case report
Serdal Ugurlu1, Ertugrul Bolayir, Ferhan Candan
1Department of Medicine, Medical Faculty, University of Cumhuriyet, Sivas, Turkey. drs_ugurlu@yahoo.com
Acta Reumatologica Portuguesa
|April 15, 2009
Summary
Familial Mediterranean fever (FMF) and multiple sclerosis (MS) are rare coexisting conditions. Early diagnosis and treatment are crucial for patients presenting with neurological symptoms suggestive of MS.
Area of Science:
- Neurology
- Immunology
- Genetics
Background:
- Familial Mediterranean fever (FMF) is a genetic autoinflammatory disorder.
- Multiple sclerosis (MS) is a chronic autoimmune disease affecting the central nervous system.
Observation:
- A 30-year-old male with a history of FMF presented with left lower extremity numbness and ataxia.
- Magnetic resonance imaging (MRI) revealed multiple sclerosis plaques in the brain and spinal cord.
Findings:
- The patient was diagnosed with coexisting FMF and MS.
- Steroid treatment was initiated for the multiple sclerosis diagnosis.
Implications:
- The rare coexistence of FMF and MS necessitates heightened clinical suspicion.
- Prompt recognition and management of MS in FMF patients are essential for optimal outcomes.
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