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Updated: Jun 24, 2026

Screening Foodstuffs for Class 1 Integrons and Gene Cassettes
Published on: June 19, 2015
Four novel resistance integron gene-cassette occurrences in bacterial isolates from zhenjiang, china
Huaxi Xu1, Zhaoliang Su, Shengjun Wang
1Department of Microbiology and Immunology, Institute of Clinical Laboratory Medicine, Jiangsu University, Zhenjiang, 212013, China. xuhx@ujs.edu.cn
Abstract:
Integrons, which are widely distributed among bacteria and are strongly associated with resistance, are specialized genetic elements that are capable of capturing, integrating, and mobilizing gene cassette. In this work, we investigated classes 1, 2, and 3 integrons associated integrases genes in 365 bacteria isolates, amplified and analyzed the structure of class 1 integron, detected 8 resistant gene cassettes [dfr17, aadA5, aadA1, aadA2, dhfrI, aadB, aac(6')-II, and pse-I], and found four novel gene-cassette arrays. We also found that commensal bacteria in the common microenvironment had the same integron gene cassette, which provided direct evidence that integron was an important horizontal transmission element.
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